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Timothy J. Thornton

Veröffentlichungen von Timothy J. Thornton zu Thornton, Timothy J.. ->
weitere Veröffentlichungen von Timothy J. Thornton:
Metallation of N-(Pivaloyl)- and N-(tert-Butoxycarbonyl)difluoroanilines : Regiocontrol by Fluorine in the Synthesis of 4-Methoxycarbonyl Derivatives (1990)
Quinazoline antifolate thymidylate synthase inhibitors: difluoro-substituted benzene ring analogs (1992)
Quinazoline antifolates inhibiting thymidylate synthase: 4-thio-substituted analogs (1991)
Metallation of N-(Pivaloyl)- and N-(tert-Butoxycarbonyl)difluoroanilines : Regiocontrol by Fluorine in the Synthesis of 4-Methoxycarbonyl Derivatives (1990)
Antineoplastic agents. 220. Synthesis of natural (-)-dolastatin 15 (1991)
The Synthesis and Thymidylate Synthase Inhibitory Activity of L-.gamma.-L-Linked Dipeptide and L-.gamma.-Amide Analogs of 2-Desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583) (1994)
Quinazoline antifolates inhibiting thymidylate synthase: 2-desamino derivatives with enhanced solubility and potency (1989)
Synthesis and cytotoxicity of potential tumor-inhibitory analogs of trimelamol (2,4,6-tris[(hydroxymethyl)methylamino]-1,3,5-triazine) having electron-withdrawing groups in place of methyl (1993)
Quinazoline antifolate thymidylate synthase inhibitors: 2'-Fluoro-N10-propargyl-5,8,-dideazafolic acid and derivatives with modifications in the C-2 position (1990)
Quinazoline-antifolate thymidylate synthase inhibitors: benzoyl ring modifications in the C2-methyl series (1990)
Veröffentlichungen zu Thornton, Timothy J..
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1
Thornton, Timothy J.. Metallation of N-(Pivaloyl)- and N-(tert-Butoxycarbonyl)difluoroanilines : Regiocontrol by Fluorine in the Synthesis of 4-Methoxycarbonyl Derivatives
In: Synthesis. - Stuttgart [u.a.] : Thieme Vol. 1990, No. 04 (0. 1990), p. 295-299
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1990
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2
Thornton, Timothy J.. Quinazoline antifolate thymidylate synthase inhibitors: difluoro-substituted benzene ring analogs
In: Journal of medicinal chemistry. - Easton, Pa. : American Chemical Society, ISSN 1520-4804, Vol. 35, No. 12 (1992), p. 2321-2327
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1992
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3
Thornton, Timothy J.. Quinazoline antifolates inhibiting thymidylate synthase: 4-thio-substituted analogs
In: Journal of medicinal chemistry. - Easton, Pa. : American Chemical Society, ISSN 1520-4804, Vol. 34, No. 3 (1991), p. 978-984
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1991
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4
Thornton, Timothy J.., Jarman, Michael. Metallation of N-(Pivaloyl)- and N-(tert-Butoxycarbonyl)difluoroanilines : Regiocontrol by Fluorine in the Synthesis of 4-Methoxycarbonyl Derivatives
in: Synthesis. - Stuttgart [u.a.] : Thieme, ISSN 1437-210X, Vol. 1990, No. 04 (1990), p. 295-299
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1990
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5
Pettit, George R.. Antineoplastic agents. 220. Synthesis of natural (-)-dolastatin 15
In: American Chemical Society: Journal of the American Chemical Society. - Washington, DC : American Chemical Society, ISSN 1520-5126, Vol. 113, No. 17 (1991), p. 6692-6693
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1991
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6
Bisset, Graham M. F.. The Synthesis and Thymidylate Synthase Inhibitory Activity of L-.gamma.-L-Linked Dipeptide and L-.gamma.-Amide Analogs of 2-Desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid...
In: Journal of medicinal chemistry. - Easton, Pa. : American Chemical Society, ISSN 1520-4804, Vol. 37, No. 20 (1994), p. 3294-3302
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1994
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7
Jones, Terence R.. Quinazoline antifolates inhibiting thymidylate synthase: 2-desamino derivatives with enhanced solubility and potency
In: Journal of medicinal chemistry. - Easton, Pa. : American Chemical Society, ISSN 1520-4804, Vol. 32, No. 4 (1989), p. 847-852
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1989
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8
Jarman, Michael. Synthesis and cytotoxicity of potential tumor-inhibitory analogs of trimelamol (2,4,6-tris[(hydroxymethyl)methylamino]-1,3,5-triazine) having electron-withdrawing groups in...
In: Journal of medicinal chemistry. - Easton, Pa. : American Chemical Society, ISSN 1520-4804, Vol. 36, No. 26 (1993), p. 4195-4200
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1993
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9
Jackman, Ann L.. Quinazoline antifolate thymidylate synthase inhibitors: 2'-Fluoro-N10-propargyl-5,8,-dideazafolic acid and derivatives with modifications in the C-2 position
In: Journal of medicinal chemistry. - Easton, Pa. : American Chemical Society, ISSN 1520-4804, Vol. 33, No. 11 (1990), p. 3067-3071
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1990
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10
Marsham, Peter R.., Jackman, Ann L.., ... Quinazoline-antifolate thymidylate synthase inhibitors: benzoyl ring modifications in the C2-methyl series
In: Journal of medicinal chemistry. - Easton, Pa. : American Chemical Society, ISSN 1520-4804, Vol. 33, No. 11 (1990), p. 3072-3078
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1990