A CD4<sup>+</sup> T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease
in: Nature medicine . - New York, NY : Nature America Inc., ISSN 1546-170X, Vol. 10, No. 4 (2004), p. 406-410 Zugang:
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2004
Many human T-cell responses specific for epitopes in Plasmodium falciparum have been described, but none has yet been shown to be predictive of protection against natural malaria infection. Here we report a peptide-specific T-cell assay that is strongly associated with protection of humans in The... mehr