Veröffentlichungen zu Sigurdsson, Helgi | ||||||||||||||
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Agnarsson, Bjarni A., Jonasson, Jon G., ... |
Inherited BRCA2 mutation associated with high grade breast cancer in: Breast cancer research and treatment , ISSN 1573-7217, Vol. 47 (2. 1998), p. 121-127 Zugang: zum Volltext ähnliche Vorschläge |
1998 | |||||||||||
Abstract Inheritance is believed to play a major role in 5–10% of breast cancer. The breast cancer susceptibility genes BRCA1 and BRCA2 are estimated to account for more than half of these cases. Recent studies have suggested that breast cancers associated with BRCA1 germline mutations are of... mehr
Copyright: Copyright 1998 Kluwer Academic Publishers mehr
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Fernö, Mårten, Baldetorp, Bo, ... |
Recurrence-free survival in breast cancer improved by adjuvant tamoxifen -especially for progesterone receptor positive tumors with a high proliferation in: Breast cancer research and treatment , ISSN 1573-7217, Vol. 36 (1. 1995), p. 23-34 Zugang: zum Volltext ähnliche Vorschläge |
1995 | |||||||||||
Summary Although the beneficial effect on breast cancer of adjuvant tamoxifen (TAM) is well established, in the series studied by our group this effect seems to have been restricted to patients with steroid receptor (especially progesterone receptor (PgR)) positive tumors. However, as some... mehr
Copyright: Copyright 1995 Kluwer Academic Publishers mehr
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Amundadottir, Laufey T, Sulem, Patrick, ... |
A common variant associated with prostate cancer in European and African populations in: Nature genetics . - New York, NY : Nature America, ISSN 1546-1718, Vol. 38, No. 6 (2006), p. 652-658 Zugang: zum Volltext ähnliche Vorschläge |
2006 | |||||||||||
With the increasing incidence of prostate cancer, identifying common genetic variants that confer risk of the disease is important. Here we report such a variant on chromosome 8q24, a region initially identified through a study of Icelandic families. Allele −8 of the microsatellite DG8S737 was... mehr
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Stacey, Simon N, Manolescu, Andrei, ... |
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor–positive breast cancer in: Nature genetics . - New York, NY : Nature America, ISSN 1546-1718, Vol. 39, No. 7 (2007), p. 865-869 Zugang: zum Volltext ähnliche Vorschläge |
2007 | |||||||||||
Familial clustering studies indicate that breast cancer risk has a substantial genetic component. To identify new breast cancer risk variants, we genotyped approximately 300,000 SNPs in 1,600 Icelandic individuals with breast cancer and 11,563 controls using the Illumina Hap300 platform. We then... mehr
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