Transgenic Corn Plants Expressing MDMV Strain B Coat Protein are Resistant to Mixed Infections of Maize Dwarf Mosaic Virus and Maize Chlorotic Mottle Virus
in: Nature biotechnology . - New York, NY : Nature America, ISSN 1546-1696, Vol. 11, No. 12 (1993), p. 1559-1564 Zugang:
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1993
The maize dwarf mosaic virus strain B (MDMV-B) coat protein (cp) gene was cloned into a monocot expression cassette and introduced into sweet corn cell suspension cultures via particle bombardment or electroporation. Transformed cells were selected on culture media containing 300 mg/l kanamycin,... mehr
A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
in: Nature . - London [u.a.] : Nature Publising Group, ISSN 1476-4687, Vol. 409, No. 6822 (2001), p. 928-933 Zugang:
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2001
We describe a map of 1.42 million single nucleotide polymorphisms (SNPs) distributed throughout the human genome, providing an average density on available sequence of one SNP every 1.9 kilobases. These SNPs were primarily discovered by two projects: The SNP Consortium and the analysis of clone... mehr
A second generation human haplotype map of over 3.1 million SNPs
in: Nature . - London [u.a.] : Nature Publising Group, ISSN 1476-4687, Vol. 449, No. 7164 (2007), p. 851-861 Zugang:
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2007
We describe the Phase II HapMap, which characterizes over 3.1 million human single nucleotide polymorphisms (SNPs) genotyped in 270 individuals from four geographically diverse populations and includes 25–35% of common SNP variation in the populations surveyed. The map is estimated to capture... mehr
Genome-wide detection and characterization of positive selection in human populations
in: Nature . - London [u.a.] : Nature Publising Group, ISSN 1476-4687, Vol. 449, No. 7164 (2007), p. 913-918 Zugang:
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2007
With the advent of dense maps of human genetic variation, it is now possible to detect positive natural selection across the human genome. Here we report an analysis of over 3 million polymorphisms from the International HapMap Project Phase 2 (HapMap2). We used ‘long-range haplotype’... mehr