THE DEHYDROGENATION OF GITOGENIN
In: American Chemical Society: Journal of the American Chemical Society. - Washington, DC : American Chemical Society, ISSN 1520-5126, Vol. 56, No. 6 (1934), p. 1424-1425 Zugang:
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Structural isomerization of (bis(trimethylsilyl)amino)phosphine oxides
In: Inorganic chemistry. - Washington, DC : American Chemical Society, ISSN 1520-510X, Vol. 17, No. 7 (1978), p. 1880-1882 Zugang:
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Molecular weights of apoprotein B obtained from human low-density lipoprotein (apoprotein B-PI) and from rat very low density lipoprotein (apoprotein B-PIII)
In: Biochemistry. - Columbus, Ohio : American Chemical Society, ISSN 1520-4995, Vol. 24, No. 6 (1985), p. 1569-1578 Zugang:
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The Use of Nonradiolabelled Steroid Infusions to Investigate the Origin of Oestrone Sulphate in Postmenopausal Women
In: Hormone and metabolic research. - Stuttgart [u.a.] : Thieme Vol. 18, No. 11 (11. 1986), p. 779-783 Zugang:
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1986
Infusion of nonradiolabelled dehydroepiandrosterone sulphate (DHA-S) has been used to investigate the possible formation of oestrone sulphate via a sulpha ted conjugate of androstenedione. The metabolic clearance rate (MCR) of DHA-S also was measured and the mean value (25 1/24h) was similar to... mehr
Crystal structure of GyrA intein from Mycobacterium xenopi reveals structural basis of protein splicing
in: Nature structural biology . - New York, NY : Nature America, ISSN 1072-8368, Vol. 5, No. 1 (1998), p. 31-36 Zugang:
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1998
Several genes from prokaryotes and lower eukaryotes have been found to contain an in-frame open reading frame, which encodes for an internal protein (intein). Post-translationally, the internal polypeptide auto-splices and ligates the external sequences to yield a functional external protein... mehr
Enzymic Characterization of the Target for Isoniazid in Mycobacterium tuberculosis
In: Biochemistry. - Columbus, Ohio : American Chemical Society, ISSN 1520-4995, Vol. 34, No. 26 (1995), p. 8235-8241 Zugang:
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The plasma concentration of oestrone sulphate in postmenopausal women: Lack of diurnal variation, effect of ovariectomy, age and weight
in: Journal of Steroid Biochemistry, in: Journal of Steroid Biochemistry . - Amsterdam : Elsevier, ISSN 0022-4731, ZDB-ID 2198730-0 Vol. 14, No. 11 (1981), p. 1101-1105
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1981
Copyright: Copyright (c) 2002 Elsevier Science B.V. mehr
Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis
in: Nature structural biology . - New York, NY : Nature America, ISSN 1072-8368, Vol. 7, No. 8 (2000), p. 663-668 Zugang:
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2000
Isocitrate lyase (ICL) plays a pivotal role in the persistence of Mycobacterium tuberculosis in mice by sustaining intracellular infection in inflammatory macrophages. The enzyme allows net carbon gain by diverting acetyl-CoA from β-oxidation of fatty acids into the glyoxylate shunt pathway.... mehr
Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid
in: Nature medicine . - New York, NY : Nature America Inc., ISSN 1546-170X, Vol. 12, No. 9 (2006), p. 1027-1029 Zugang:
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2006
Isoniazid is one of the most effective antituberculosis drugs, yet its precise mechanism of action is still controversial. Using specialized linkage transduction, a single point mutation allele (S94A) within the putative target gene inhA was transferred in Mycobacterium tuberculosis. The... mehr
Niacin deficiency increases the sensitivity of rats to the short and long term effects of ethylnitrosourea treatment
in: Molecular and cellular biochemistry , ISSN 1573-4919, Vol. 193 (1/2. 1999), p. 83-87 Zugang:
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1999
Abstract Most chemotherapy agents function by causing damage to the DNA of rapidly dividing cells, such as those in the bone marrow, leading to anemia and leukopenia during chemotherapy and the development of secondary leukemias in the years following recovery from the original disease. We... mehr
Copyright: Copyright 1999 Kluwer Academic Publishers mehr
Evidence from Turner's syndrome of an imprinted X-linked locus affecting cognitive function
in: Nature . - London [u.a.] : Nature Publising Group, ISSN 1476-4687, Vol. 387, No. 6634 (1997), p. 705-708 Zugang:
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1997
Turner's syndrome is a sporadic disorder of human females in which all or part of one X chromosome is deleted. Intelligence is usually normal but social adjustment problems are common. Here we report a study of 80 females with Turner's syndrome and a single X chromosome, in 55 of which the X was... mehr
Persistence of Mycobacterium tuberculosis in macrophages and micerequires the glyoxylate shunt enzyme isocitrate lyase
in: Nature . - London [u.a.] : Nature Publising Group, ISSN 1476-4687, Vol. 406, No. 6797 (2000), p. 735-738 Zugang:
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2000
Mycobacterium tuberculosis claims more human lives each year thanany other bacterial pathogen. Infection is maintained in spite of acquiredimmunity and resists eradication by antimicrobials. Despitean urgent need for new therapies targeting persistent bacteria, our knowledgeof bacterial... mehr