Anmelden/Registrieren
Erscheinungsjahr:
 
Zurück zur geteilten Ansicht
Laurence H. Hurley

Veröffentlichungen von Laurence H. Hurley zu Hurley, Laurence H.. ->
weitere Veröffentlichungen von Laurence H. Hurley:
Elucidation and formulation of novel biosynthetic pathways leading to the pyrrolo[1,4]benzodiazepine antibiotics anthramycin, tomaymycin, and sibiromycin (1980)
Biosynthesis of anthramycin. Determination of the labeling pattern by the use of radioactive and stable isotope techniques (1975)
DNA and associated targets for drug design (1989)
Molecular basis for sequence-specific DNA alkylation by CC-1065 (1988)
Covalent binding of antitumor antibiotics in the minor groove of DNA. Mechanism of action of CC-1065 and the pyrrolo(1,4)benzodiazepines (1986)
Pyrrolo[1,4]benzodiazepine antibiotics. Biosynthetic conversion of tyrosine to the C2- and C3-proline moieties of anthramycin, tomaymycin, and sibiromycin (1979)
Pyrrolo[1,4]benzodiazepine antibiotics. Biosynthesis of the antitumor antibiotic sibiromycin by Streptosporangium sibiricum (1979)
Pyrrolo[1,4]benzodiazepine antibiotics. Biosynthesis of the antitumor antibiotic 11-demethyltomaymycin and its biologically inactive metabolite oxotomaymycin by Streptomyces achromogenes (1976)
Analysis of the monoalkylation and cross-linking sequence specificity of bizelesin, a bifunctional alkylation agent related to (+)-CC-1065 (1993)
Structure-activity relationships of (+)-CC-1065 analogs in the inhibition of helicase-catalyzed unwinding of duplex DNA (1992)
Cooperative Bending of the 21-Base-Pair Repeats of the SV40 Viral Early Promoter by Human Sp1 (1994)
Effect of the (+)-CC-1065-(N3-adenine)DNA adduct on in vitro DNA synthesis mediated by Escherichia coli DNA polymerase (1992)
Determination of the major tautomeric form of the covalently modified adenine in the (+)-CC-1065-DNA adduct by proton and nitrogen-15 NMR studies (1990)
Construction and characterization of a site-directed CC-1065-N3-adenine adduct within a 117 base pair DNA restriction fragment (1986)
Anthramycin binding to deoxyribonucleic acid-mytomycin C complexes. Evidence for drug-induced DNA conformational change and cooperativity in mitomycin C binding (1981)
Veröffentlichungen zu Hurley, Laurence H..
Zurück zur geteilten Ansicht
Verfasser Titel Jahr absteigend sortierenaufsteigend sortieren
zeige Details
1
Hurley, Laurence H.. Elucidation and formulation of novel biosynthetic pathways leading to the pyrrolo[1,4]benzodiazepine antibiotics anthramycin, tomaymycin, and sibiromycin
In: Accounts of chemical research. - Columbus, Ohio : American Chemical Soc., ISSN 1520-4898, Vol. 13, No. 8 (1980), p. 263-269
Zugang: zum Volltext
ähnliche Vorschläge
1980
zeige Details
2
Hurley, Laurence H.. Biosynthesis of anthramycin. Determination of the labeling pattern by the use of radioactive and stable isotope techniques
In: American Chemical Society: Journal of the American Chemical Society. - Washington, DC : American Chemical Society, ISSN 1520-5126, Vol. 97, No. 15 (1975), p. 4372-4378
Zugang: zum Volltext
ähnliche Vorschläge
1975
zeige Details
3
Hurley, Laurence H.. DNA and associated targets for drug design
In: Journal of medicinal chemistry. - Easton, Pa. : American Chemical Society, ISSN 1520-4804, Vol. 32, No. 9 (1989), p. 2027-2033
Zugang: zum Volltext
ähnliche Vorschläge
1989
zeige Details
4
Hurley, Laurence H.. Molecular basis for sequence-specific DNA alkylation by CC-1065
In: Biochemistry. - Columbus, Ohio : American Chemical Society, ISSN 1520-4995, Vol. 27, No. 10 (1988), p. 3886-3892
Zugang: zum Volltext
ähnliche Vorschläge
1988
zeige Details
5
Hurley, Laurence H.. Covalent binding of antitumor antibiotics in the minor groove of DNA. Mechanism of action of CC-1065 and the pyrrolo(1,4)benzodiazepines
In: Accounts of chemical research. - Columbus, Ohio : American Chemical Soc., ISSN 1520-4898, Vol. 19, No. 8 (1986), p. 230-237
Zugang: zum Volltext
ähnliche Vorschläge
1986
zeige Details
6
Hurley, Laurence H.. Pyrrolo[1,4]benzodiazepine antibiotics. Biosynthetic conversion of tyrosine to the C2- and C3-proline moieties of anthramycin, tomaymycin, and sibiromycin
In: Biochemistry. - Columbus, Ohio : American Chemical Society, ISSN 1520-4995, Vol. 18, No. 19 (1979), p. 4230-4237
Zugang: zum Volltext
ähnliche Vorschläge
1979
zeige Details
7
Hurley, Laurence H.. Pyrrolo[1,4]benzodiazepine antibiotics. Biosynthesis of the antitumor antibiotic sibiromycin by Streptosporangium sibiricum
In: Biochemistry. - Columbus, Ohio : American Chemical Society, ISSN 1520-4995, Vol. 18, No. 19 (1979), p. 4225-4229
Zugang: zum Volltext
ähnliche Vorschläge
1979
zeige Details
8
Hurley, Laurence H.. Pyrrolo[1,4]benzodiazepine antibiotics. Biosynthesis of the antitumor antibiotic 11-demethyltomaymycin and its biologically inactive metabolite oxotomaymycin by Streptomyces...
In: Biochemistry. - Columbus, Ohio : American Chemical Society, ISSN 1520-4995, Vol. 15, No. 17 (1976), p. 3760-3769
Zugang: zum Volltext
ähnliche Vorschläge
1976
zeige Details
9
Sun, Daekyu. Analysis of the monoalkylation and cross-linking sequence specificity of bizelesin, a bifunctional alkylation agent related to (+)-CC-1065
In: American Chemical Society: Journal of the American Chemical Society. - Washington, DC : American Chemical Society, ISSN 1520-5126, Vol. 115, No. 14 (1993), p. 5925-5933
Zugang: zum Volltext
ähnliche Vorschläge
1993
zeige Details
10
Sun, Daekyu. Structure-activity relationships of (+)-CC-1065 analogs in the inhibition of helicase-catalyzed unwinding of duplex DNA
In: Journal of medicinal chemistry. - Easton, Pa. : American Chemical Society, ISSN 1520-4804, Vol. 35, No. 10 (1992), p. 1773-1782
Zugang: zum Volltext
ähnliche Vorschläge
1992
zeige Details
11
Sun, Daekyu. Cooperative Bending of the 21-Base-Pair Repeats of the SV40 Viral Early Promoter by Human Sp1
In: Biochemistry. - Columbus, Ohio : American Chemical Society, ISSN 1520-4995, Vol. 33, No. 32 (1994), p. 9578-9587
Zugang: zum Volltext
ähnliche Vorschläge
1994
zeige Details
12
Sun, Daekyu. Effect of the (+)-CC-1065-(N3-adenine)DNA adduct on in vitro DNA synthesis mediated by Escherichia coli DNA polymerase
In: Biochemistry. - Columbus, Ohio : American Chemical Society, ISSN 1520-4995, Vol. 31, No. 10 (1992), p. 2822-2829
Zugang: zum Volltext
ähnliche Vorschläge
1992
zeige Details
13
Lin, Chin Hsiung. Determination of the major tautomeric form of the covalently modified adenine in the (+)-CC-1065-DNA adduct by proton and nitrogen-15 NMR studies
In: Biochemistry. - Columbus, Ohio : American Chemical Society, ISSN 1520-4995, Vol. 29, No. 41 (1990), p. 9503-9507
Zugang: zum Volltext
ähnliche Vorschläge
1990
zeige Details
14
Needham-VanDevanter, Donald R.. Construction and characterization of a site-directed CC-1065-N3-adenine adduct within a 117 base pair DNA restriction fragment
In: Biochemistry. - Columbus, Ohio : American Chemical Society, ISSN 1520-4995, Vol. 25, No. 26 (1986), p. 8430-8436
Zugang: zum Volltext
ähnliche Vorschläge
1986
zeige Details
15
Kaplan, David J.. Anthramycin binding to deoxyribonucleic acid-mytomycin C complexes. Evidence for drug-induced DNA conformational change and cooperativity in mitomycin C binding
In: Biochemistry. - Columbus, Ohio : American Chemical Society, ISSN 1520-4995, Vol. 20, No. 26 (1981), p. 7572-7580
Zugang: zum Volltext
ähnliche Vorschläge
1981
zeige Details
16
Warpehoski, Martha A.. Sequence selectivity of DNA covalent modification
In: Chemical research in toxicology. - New York, NY : ACS Publ., ISSN 1520-5010, Vol. 1, No. 6 (1988), p. 315-333
Zugang: zum Volltext
ähnliche Vorschläge
1988
zeige Details
17
Hurley, Laurence H., Petrusek, Ruby Proposed structure of the anthramycin–DNA adduct
in: Nature . - London [u.a.] : Nature Publising Group, ISSN 1476-4687, Vol. 282, No. 5738 (1979), p. 529-531
Zugang: zum Volltext
ähnliche Vorschläge
1979
zeige Details
18
Henderson, Douglas, Hurley, Laurence H. Molecular struggle for transcriptional control
in: Nature medicine . - New York, NY : Nature America Inc., ISSN 1546-170X, Vol. 1, No. 6 (1995), p. 525-527
Zugang: zum Volltext
ähnliche Vorschläge
1995
zeige Details
19
Hurley, Laurence H.., Sun, Daekyu. (+)-CC-1065 as a probe for intrinsic and protein-induced bending of DNA
in: Journal of Molecular Recognition, in: Journal of Molecular Recognition . - Chicester [u.a.] : Wiley, ISSN 0952-3499, ZDB-ID 1491198-x Vol. 7 (2. 1994), p. 123-132
Zugang: zum Volltext
ähnliche Vorschläge
1994
zeige Details
20
Henderson, Douglas., Hurley, Laurence H.. Specific targeting of protein-DNA complexes by dna-reactive drugs (+)-CC-1065 and pluramycins
in: Journal of Molecular Recognition, in: Journal of Molecular Recognition . - Chicester [u.a.] : Wiley, ISSN 0952-3499, ZDB-ID 1491198-x Vol. 9 (2. 1996), p. 75-87
Zugang: zum Volltext
ähnliche Vorschläge
1996