Changes in Muscular Glycogen Synthetase Activity following Denervation
in: Nature . - London [u.a.] : Nature Publising Group, ISSN 1476-4687, Vol. 211, No. 5047 (1966), p. 416-417 Zugang:
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1966
Hines and Knowlton1,2 have demonstrated a decrease of muscular glycogen levels after denervation. The biochemical mechanism underlying this phenomenon, however, is not clearly understood. It does not seem to be explained by an activation of phosphorolytic processes, as phosphorylase was shown by... mehr
Skeletal muscle glycogenosis type II: Biochemical and electron microscopic investigations of one case
in: Journal of neurology , ISSN 1432-1459, Vol. 201 (2. 1972), p. 98-108 Zugang:
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1972
Summary A 7 year-old boy suffering since early infancy from muscular weakness with diffuse hypotrophy and hypotonia is described. There was a remarkable intellectual retardation, but not hepato or cardiomegaly. A muscle biopsy revealed large quantities of glycogen stored inside the muscular... mehr Zusammenfassung Es wird ein 7jähriger Knabe beschrieben, welcher seit früher Kindheit eine Muskelschwäche mit diffuser Hypotrophie und Hypotonie aufwies. Psychischer Entwicklungsrückstand, aber keine Hepato- oder Kardiomegalie. Eine Muskelbiopsie zeigte große Mengen von Glykogen innerhalb... mehr
The metabolism of cyclic-3′-5′-adenosine monophosphate (cAMP) in diseased muscle
in: Journal of neurology , ISSN 1432-1459, Vol. 208 (4. 1975), p. 259-265 Zugang:
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1975
Summary Adenyl cyclase (AC) and cyclic nucleotide phosphodiesterase (PDE) have been studied in muscle from patients affected with muscular and neuromuscular diseases as well as in muscle of rats after experimental denervation. A diminution of AC was observed in Duchenne's dystrophy, in neurogenic... mehr Zusammenfassung In Muskeln von Patienten mit verschiedenen neuromuskulären Erkrankungen sowie am experimentell denervierten Rattenmuskel wurden die Adenylcyclase (AC) und die cyclische Nucleotidphosphodiesterase (PDE) bestimmt. Eine Verminderung der AC wurde in der Duchenneschen... mehr
Evaluation by somatosensory evoked potentials of the neurotoxicity of cisplatin alone or in combination with glutathione
in: Neurological sciences , ISSN 1590-3478, Vol. 13 (8. 1992), p. 643-647 Zugang:
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1992
Abstract The use of high doses of cisplatin (DDP) in the treatment of different solid tumors is often prevented by the onset of a disabling sensory neuropathy. In an attempt to minimize DDP-induced neurotoxicity different schedules of DDP administration have been tested. Moreover, during the past... mehr Sommario L'uso di alte dosi di cisplatino (DDP) nel trattamento di diversi tipi di tumore solido è spesso impedito dalla insorgenza di una grave neuropatia periferica. Nel tentativo di ridurre l'incidenza di questa complicanza sono state sperimentate diverse, modalità di somministrazione del... mehr
Copyright: Copyright 1992 Masson Italia Periodici S.r.l. mehr
Carboplatin toxic effects on the peripheral nervous system of the rat
in: Annals of oncology , ISSN 1569-8041, Vol. 9 (4. 1998), p. 443-447 Zugang:
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1998
Abstract Background: The most striking of carboplatin's advantages (CBDCA) over cisplatin (CDDP) is its markedly reduced rate of neurotoxic effects. However, the use of CBDCA higher-intensity schedules and the association with other neurotoxic drugs in polychemotherapy may cause some concern... mehr
Copyright: Copyright 1998 Kluwer Academic Publishers mehr
Biochemical and morphological changes induced by Triton-X 100 in skeletal muscle of rats after abdominal aorta ligation
in: Cellular and molecular life sciences , ISSN 1420-9071, Vol. 29 (6. 1973), p. 681-682 Zugang:
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1973
Riassunto Il Triton-X 100 somministrato in vivo a ratti dopo legatura dell'aorta addominale provoca l'aumento di alcuni enzimi lisosomiali e la comparsa di focolai necrotici nei muscoli degli arti posteriori, simili a quelli osservabili nelle lesioni di tipo ischemico. mehr
Choline acetyltransferase activity in human muscular diseases
in: Journal of neurology , ISSN 1432-1459, Vol. 211 (2. 1976), p. 189-192 Zugang:
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1976
Zusammenfassung Die Cholinacetyltransferase-Aktivität wurde in Muskeln von Patienten mit Neuromyopathien gemessen. Die Muskelbiopsien wurden bei Patienten mit Myasthenia gravis, mit verschiedenen neurogenen Atrophien der Muskeln und mit Muskeldystrophie vom geschlechtsgebundenen Typus entnommen.... mehr
Encephalomyelitis with thyrotoxicosis
in: Journal of neurology , ISSN 1432-1459, Vol. 218 (4. 1978), p. 293-295 Zugang:
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1978
Summary A case of thyrotoxicosis associated with neuropathy and encephalomyelitis is reported which gradually improved as regards the hyperthyroidism and the neurological deficit during treatment with Tapazole. The possible role of the nervous system of an excess of thyroxine or an autoimmune... mehr
Association between microtubules and mitochondria in myelinated axons of Lacerta muralis
in: Cell & tissue research , ISSN 1432-0878, Vol. 245 (1. 1986), p. 1-8 Zugang:
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1986
Summary The spatial relationship between microtubules and mitochondria was studied in myelinated axons of the ventral and dorsal spinal roots of the lizard Lacerta muralis by use of quantitative methods in single and serial sections. Microtubules mainly occurred in groups of 3 to 10. The mean... mehr
An electron microscope study of quantitative relationships between axon and Schwann cell sheath in myelinated fibres of peripheral nerves
in: Anatomy and embryology , ISSN 1432-0568, Vol. 175 (4. 1987), p. 423-430 Zugang:
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1987
Summary The quantitative relationships between the crossectional area of the Schwann cell sheath (myelin included) and that of its related axon were studied by electron microscopy in the nerve fibres of the spinal roots of lizard (Lacerta muralis). In both ventral and dorsal roots the... mehr
Lipid changes in neurogenic muscular atrophies
in: Research in experimental medicine , ISSN 1433-8580, Vol. 164 (3. 1974), p. 241-246 Zugang:
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1974
Summary Lipid composition of muscles of 14 patients with neurogenic muscular atrophies was determined, and compared statistically to that of 8 normal controls. The neurogenic muscular atrophies show no alteration in the lipid content, but single phospholipid fractions were modified. The lecithin... mehr
Modifications of diazepam binding inhibitor and peripheral benzodiazepine receptors in the lymphocytes of epileptic patients
in: Neurological sciences , ISSN 1590-3478, Vol. 17 (2. 1996), p. 141-145 Zugang:
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1996
Abstract Recent experimental evidence has suggested that peripheral benzodiazepine receptors (PBR) may play a role in epilepsy and antiepileptic drug action. Since PBR are also present in circulating lymphocytes, and may interact with anticonvulsant drugs, this study was designed to look for... mehr Sommario Recenti dati sperimentali hanno evidenziato che i recettori periferici delle benzodiazepine (PBR) possono ricoprire un ruolo nell'epilessia e nell'azione dei farmaci antiepilettici. Poiché i PBR sono presenti anche sui linfociti in circolo, dove è stato dimostrato che possono... mehr
Reduced platelet glutamate uptake in Parkinson's disease
in: Journal of neural transmission , ISSN 1435-1463, Vol. 106 (7/8. 1999), p. 685-692 Zugang:
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1999
Summary. Defects in mitochondrial enzymes have been found not only in substantia nigra, but also in platelets from Parkinson's Disease (PD) patients, suggesting a systemic impairment of energy metabolism. Since platelets present an energy-dependent glutamate uptake similar to that described in... mehr
Copyright: Copyright 1999 Springer-Verlag Wien mehr
Acute noise stress in rats increases the levels of diazepam binding inhibitor (DBI) in hippocampus and adrenal gland
in: Psychopharmacology , ISSN 1432-2072, Vol. 103 (3. 1991), p. 339-342 Zugang:
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1991
Abstract We investigated the effect of acute noise-induced stress on the concentrations of diazepam binding inhibitor (DBI) and its processing products in brain regions and adrenal glands of rats. DBI levels in hippocampus began to increase at 15 and 30 min and became significantly higher (+100%)... mehr
Fourth metting of the European Neurological Society 25–29 June 1994 Barcelona, Spain
in: Journal of neurology , ISSN 1432-1459, Vol. 241 (1. 1994), p. 1-164 Zugang:
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