Effectiveness of murine leukemia chemotherapy according to the immune state
in: Cancer immunology immunotherapy , ISSN 1432-0851, Vol. 2 (2. 1977), p. 139-141 Zugang:
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1977
Summary Cyclophosphamide (CPM) chemotherapy (134 mg/kg) of L1210 leukemia is less efficient in mice previously immunodepressed by anti-thymocyte serum (ATS) than in non-ATS pre-treated mice. On the other hand, administration of a higher dose of CPM (403 mg/kg), which kills a greater number of... mehr
Comparative pharmacology of three new nitrosourea analogues: RFCNU, RPCNU, and chlorozotocin
in: Cancer chemotherapy and pharmacology , ISSN 1432-0843, Vol. 3 (4. 1979), p. 217-221 Zugang:
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1979
Summary We have compared the LD50 of three new nitrosourea derivatives, RFCNU, RPCNU, and chlorozotocin (CZT), in L1210 leukemia-bearing mice: CZT is the most toxic and RFCNU the least. We studied the oncostatic effect of different doses, varying from 5 mg to 150 mg/kg, given three times on the... mehr