The SCL/TAL1 gene: Roles in normal and malignant haematopoiesis
in: BioEssays, in: BioEssays . - New York, NY : Wiley-Liss, ISSN 0265-9247, ZDB-ID 1473795-4 Vol. 19 (7. 1997), p. 607-613
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1997
SCL (TAL1/TCL5) is a member of the helix-loop-helix family of transcription factors. Originally identified because of its involvement in a tumour-specific chromosomal translocation, overexpression of the SCL gene is the most common molecular abnormality found in human T cell leukaemia. Transgenic... mehr
Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation
in: Nature medicine . - New York, NY : Nature America Inc., ISSN 1546-170X, Vol. 4, No. 3 (1998), p. 303-308 Zugang:
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1998
During early pregnancy, in response to the implanting embryo, the surrounding uterine stroma undergoes a dramatic transformation into a specialized tissue known as the decidua. The de-cidua encapsulates the developing embryo, facilitating nutrient transfer and limiting tro-phoblast invasion. Here... mehr
Localization of murine HLH gene NSCL to Chromosome 1 by use of recombinant inbred strains
in: Mammalian genome , ISSN 1432-1777, Vol. 3 (3. 1992), p. 182-183 Zugang:
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1992
Copyright: Copyright 1992 Springer-Verlag New York Inc mehr
Genome-wide association study identifies novel breast cancer susceptibility loci
in: Nature . - London [u.a.] : Nature Publising Group, ISSN 1476-4687, Vol. 447, No. 7148 (2007), p. 1087-1093 Zugang:
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2007
Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility to the disease. Known susceptibility genes account for less than 25% of the familial risk of breast cancer, and the residual genetic variance is likely to be due to variants conferring more moderate... mehr