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Verfasser Titel Jahr
zeige Details Hart, Ian R. ‘Seed and soil’ revisited: mechanisms of site-specific metastasis
in: Cancer and metastasis reviews , ISSN 1573-7233, Vol. 1 (1. 1982), p. 5-16
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1982
Summary Clinical studies have shown that malignant tumors frequently show definite metastatic patterns. This tendency for neoplasms of a particular histologic type to metastasize to a specific organ is also a characteristic of experimental animal tumor systems. Mechanical entrapment, arrest determined by specific recognition between neoplastic cells and capillaries and organ-determined modulation of tumor growth have all been suggested as mechanisms that regulate this specificity. Experimental evidence for the role that each of these mechanisms plays in the regulation of metastatic patterns of transplantable rodent tumors is discussed in this review.
Copyright: Copyright 1982 Martinus Nijhoff Publishers
beteiligte Personen: Hart, Ian R.
Format: Elektronisch
Erschienen: 1982.
Serie: Springer Online Journal Archives 1860-2000 [Dig. Serial]
Schlagwörter:
URL: http://dx.doi.org/10.1007/BF00049477

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